When it comes to glowing, youthful skin, topical products are only part of the equation. According to Dr. Doris Day, certain supplements can play a key role in supporting skin health from the inside out. Here are five that she recommends adding to your routine.

1. Magnesium Glycinate
Magnesium glycinate isn’t just for relaxation and sleep — it also helps reduce inflammation and supports healthy cortisol levels. Since chronic stress and inflammation can accelerate skin aging, keeping magnesium levels balanced may help your skin stay calmer, clearer, and more resilient.

2. Urolithin A
Urolithin A is a supplement that supports mitochondrial health — essentially your cells’ energy factories. “This helps with cellular energy, which in turn aids cell repair,” says Dr. Day. By supporting your skin’s natural repair processes, urolithin A can contribute to a healthier, more vibrant complexion.

3. Vitamin D with Vitamin K
Vitamin D plays a critical role in barrier support and immune protection, both for your skin and your overall health. Pairing it with vitamin K helps improve absorption and ensures you get the full benefit. “Vitamin D is essential for skin function, and vitamin K enhances its effectiveness,” Dr. Day explains.

4. Genistein
Genistein is a plant-derived compound that can boost collagen production — a key factor in maintaining skin firmness and elasticity. “I think it’s underrated and incredibly helpful for the skin,” says Dr. Day. Adding genistein to your routine may support a plumper, more youthful-looking complexion.

5. Creatine
While often associated with athletic performance, creatine also supports cellular energy and hydration in the skin. By helping skin cells maintain energy and moisture, creatine can contribute to a smoother, more supple texture.
The Bottom Line
These supplements are all readily available in various forms, and when combined with a balanced diet, consistent skincare, and proper sun protection, they can make a noticeable difference in skin health.
Dr. Day emphasizes that true skin wellness comes from a holistic approach: “Supplements help, but pairing them with great skincare, sun protection, and a healthy lifestyle is what truly makes the difference.”

