Ultra-processed foods have already been linked to a long list of health concerns, but new research is now putting some so-called “natural” food coloring alternatives under the microscope as well. According to recent studies highlighted by The Wall Street Journal, certain food dyes derived from natural sources may still be associated with an increased risk of type 2 diabetes and even some cancers—challenging the idea that “natural” automatically means healthier.
The findings come from large-scale French studies that tracked the diets and health outcomes of more than 100,000 adults over several years. Researchers examined participants’ intake of food additives commonly found in processed snacks, drinks, desserts, yogurts, cereals, sauces, and packaged foods. Surprisingly, several natural coloring additives—including beta-carotene, curcumin, anthocyanins, and caramel coloring—were linked to higher risks of chronic disease.

Natural Food Coloring Alternatives May Be Associated With Type-2 Diabetes & Cancer
One study published in Diabetes Care found that higher consumption of certain food coloring additives was associated with a significantly greater risk of developing type 2 diabetes. Researchers observed elevated risks tied to additives such as beta-carotene, curcumin, anthocyanins, and caramel coloring, even after adjusting for lifestyle and dietary factors.
Other recent research also connected some additives and preservatives frequently used in ultra-processed foods with increased cancer risk, particularly breast cancer. Scientists emphasized that while these studies do not prove direct causation, the associations were strong enough to raise concerns about the long-term effects of chronic additive exposure.
Experts say one important takeaway is that “natural” food dyes are still heavily processed before being added to packaged foods. Although ingredients like turmeric-derived curcumin or beta-carotene may sound healthier than synthetic dyes, researchers believe the manufacturing process, concentration levels, and interaction with other additives may affect how they behave in the body.
Some scientists suspect these additives could contribute to inflammation, insulin resistance, gut microbiome disruption, or oxidative stress—all factors associated with chronic disease development. Researchers also noted that additives are rarely consumed alone, meaning combinations of dyes, preservatives, sweeteners, and emulsifiers in ultra-processed foods may collectively impact health over time.
Health experts stress that the findings should not cause panic about naturally colorful whole foods like carrots, berries, or turmeric itself. The concern centers specifically around concentrated additives used in packaged and industrially processed foods.
For consumers, nutrition experts recommend focusing less on whether a dye is “natural” or “artificial” and more on limiting ultra-processed foods overall. Choosing minimally processed meals, reading ingredient labels carefully, and prioritizing whole foods may help reduce exposure to unnecessary additives while supporting long-term metabolic health.

